旧金山发布卡痛衍生物MGM-15致命过量警报:首例死亡今年9月发生

加州旧金山公共卫生局10月21日发布健康警报,提醒医疗机构和公众注意一种卡痛衍生物类阿片——二氢-7-羟基帽柱木碱(dihydro-7-hydroxymitragynine,简称 MGM-15)。该物质为半合成卡痛衍生物类阿片,未被批准用于任何医疗用途,过量摄入可导致致命的阿片类过量。
旧金山首席法医办公室确认,今年9月下旬去世的一名成年过量死者体内检出 MGM-15,为旧金山首例。此前该物质已在犹他州和华盛顿州的过量案例中被检出。美国缉毒局已将其列为一级管制物质,销售属违法。警报称,MGM-15 被发现掺入以“猫爪草”(uncaria tomentosa)名义在烟店和加油站销售的产品中。死者使用的“Script botanicals x Maui labs”品牌包装经法医毒理学检测确认含有 MGM-15,包装上未提及卡痛或7-羟基帽柱木碱。
旧金山公共卫生局表示,首席法医办公室将继续检测包括 MGM-15 在内的新型物质,并与卫生局共享结果以指导公共卫生干预。
关联:犹他州警告:半合成卡痛制品已致4人死亡 错标产品“可能致命”
San Francisco Issues Fatal Overdose Alert for Kratom-Derived Opioid MGM-15: First Local Death Recorded in September
The San Francisco Department of Public Health issued a health alert on October 21 warning providers and the public about MGM-15 (dihydro-7-hydroxymitragynine), a semi-synthetic kratom-derived opioid not approved for any medical use that can cause fatal opioid overdose.
The Office of the Chief Medical Examiner detected MGM-15 in an adult who died in late September, the first known San Francisco case; the substance had previously been identified in overdoses in Utah and Washington. The DEA has designated MGM-15 a Schedule 1 substance, making its sale illegal. It has been found in products marketed as 'cat's claw' (uncaria tomentosa) sold at smoke shops and gas stations; forensic testing confirmed MGM-15 in the 'Script botanicals x Maui labs' product the decedent used, whose packaging made no reference to kratom or 7-hydroxymitragynine. The medical examiner's office will continue testing for novel substances including MGM-15 and share results with the health department.
来源:GSM·美国(原文链接)
图片来源:图:旧金山市政厅。图片来源:Wikimedia Commons。Photo: San Francisco City Hall. Source: Wikimedia Commons.

