犹他州警告：半合成卡痛制品已致4人死亡 错标产品“可能致命”
犹他州卫生与公众服务部近日确认，该州已有4人死于与半合成卡痛（kratom）制品相关的中毒，并警告市面上仍在销售的错标产品“可能致命”。
据《纽约邮报》10月9日报道，致死物质为两种强效半合成卡痛化合物：伪吲哚帽柱木碱（mitragynine pseudoindoxyl，简称MGPI）和二氢-7-羟基帽柱木碱（dihydro-7-hydroxymitragynine，简称MGM-15）。这些产品被包装成“猫爪”（cat's claw）等名称，在网上、烟草店、加油站及其他零售店销售。卫生部门特别点名一种名为“Buzzers”的片剂——广告宣称是“专利植物提取物混合物”。
犹他州毒物控制中心医疗主任迈克尔·莫斯医生告诉NBC新闻，4起死亡中至少有1起与使用Buzzers产品有关。而生产Buzzers的Exo Club公司则在其产品说明中坚称，产品“不含任何卡痛或常见卡痛化合物”，该公司尚未回应媒体置评请求。
卡痛是原产东南亚的热带植物，其叶片中的生物碱作用于人体阿片受体，大剂量可产生类似阿片类药物的镇静与欣快感，也因此被称为“加油站海洛因”。犹他州今年5月已立法禁止销售卡痛提取物及含半合成卡痛化合物的产品，但卫生部门警告，这些产品在一些商店仍可能买到。
值得注意的是，就在两周前，密西西比大学两名学生——18岁的艾丹·汉密尔顿和20岁的罗伯特·斯特朗在同一晚疑似过量死亡，两人身边都发现了卡痛制品。汉密尔顿去世前一周曾在一家烟草店购买了在当地非法销售的Smax Pseudo-DHM咀嚼片。
卫生官员呼吁民众不要购买或使用来路不明的卡痛类产品，出现不适立即就医并联系毒物控制中心。联邦层面，卫生部长小罗伯特·肯尼迪与FDA局长马蒂·马卡里已在2025年提议将7-羟基帽柱木碱列为一类管制药品，但天然卡痛本身尚未被列入联邦管制名单。
Utah Warns Semi-Synthetic Kratom Products Linked to 4 Deaths; Mislabeled Products "Potentially Deadly"
The Utah Department of Health and Human Services has confirmed four deaths in the state linked to semi-synthetic kratom products, warning that mislabeled products still on store shelves could be deadly.
The deaths were caused by mitragynine pseudoindoxyl (MGPI) and dihydro-7-hydroxymitragynine (MGM-15), potent semi-synthetic kratom compounds sold under names like "cat's claw" online and at smoke shops, gas stations and other retailers, the New York Post reported on October 9. The agency singled out tablets marketed as "Buzzers," advertised as a "proprietary blend of botanical extracts."
One of the four deaths resulted from use of a Buzzers product, Dr. Michael Moss, medical director of the Utah Poison Control Center, told NBC News. Exo Club, the company behind Buzzers, insists in its product description that the tablets don't contain any kratom or popular kratom compounds. The company did not immediately respond to requests for comment.
Kratom is a tropical plant native to Southeast Asia whose leaves contain alkaloids that act on the brain's opioid receptors; at high doses they can produce opioid-like sedation and euphoria, earning such products the nickname "gas station heroin." Utah banned the sale of kratom extracts and products containing semi-synthetic kratom compounds in May, but the health department warned they may still be available at some stores.
Two weeks earlier, two University of Mississippi students — Aidan Hamilton, 18, and Robert Strang, 20 — died of suspected overdoses on the same night, each with kratom products nearby. Hamilton had visited a smoke shop near campus a week before his death to buy Smax Pseudo-DHM, a chewable form of the supplement that is illegal to sell there.
Health officials urge the public not to buy or use kratom products of unknown origin and to seek medical help and contact poison control if symptoms appear. At the federal level, HHS Secretary RFK Jr. and FDA Commissioner Dr. Marty Makary proposed in 2025 making 7-hydroxymitragynine a Schedule I drug, though natural kratom itself is not currently on the federal controlled-substances list.
图片来源：CC BY-SA 3.0（Wikimedia Commons）摄影：Jkinsocal
