战争部战略资本办公室与Antheia签8000万美元有条件贷款承诺 扩产仿制药关键原料本土产能
美国战争部10月17日发布消息，该部战略资本办公室（OSC）已与生物制造企业 Antheia, Inc. 签署一项8,000万美元的有条件贷款承诺。这笔贷款将与私人资本配套，用于扩大仿制药关键起始物料（KSM）与原料药（API）在美国本土的产能。Antheia 总部位于加州 Menlo Park。
Antheia 的技术路线是用工程酵母以一步发酵把糖类转化成药物成分，替代传统上依赖植物种植与农业提取的供应方式。该公司生产的成分对应多种基本药物；战争部称，此举旨在降低美国基本药物供应链对海外来源的依赖。
战争部在新闻稿中表示，这项承诺是落实特朗普总统第13944号行政令（EO 13944）的一步，该行政令要求推动基本药物在美国本土制造。新闻稿援引战略资本办公室主任 David A. Lorch、投资董事总经理 Akshaya Trivedi 与负责研究与工程的副部长 Emil Michael 的表态，称这笔投资将强化美国医药供应链的安全与韧性。
这项承诺目前仍属有条件承诺：贷款正式交割前，Antheia 还须满足财务、法律、技术及其他尽职调查方面的条件。战略资本办公室是战争部下设的融资机构，职责是以贷款等金融工具撬动私人资本，投向与国家安全相关的关键供应链技术。（GSM 据美国战争部新闻稿整理）
Department of War's Office of Strategic Capital Signs $80 Million Conditional Loan Commitment With Antheia to Expand Domestic Production of Critical Drug Ingredients
The U.S. Department of War announced on October 17 that its Office of Strategic Capital (OSC) has signed an $80 million conditional loan commitment with biomanufacturing company Antheia, Inc. The loan, to be combined with private capital, would expand U.S. domestic production capacity for key starting materials (KSMs) and active pharmaceutical ingredients (APIs) used in generic medicines. Antheia is headquartered in Menlo Park, California.
Antheia's technology uses engineered yeast in a single-step fermentation process that converts sugar into pharmaceutical ingredients, replacing supply chains that traditionally depend on plant cultivation and agricultural extraction. The company's ingredients feed into a range of essential medicines, and the department said the financing is aimed at reducing U.S. reliance on overseas sources for them.
In its release, the department described the commitment as a step in implementing President Trump's Executive Order 13944 (EO 13944), which directs the expansion of domestic manufacturing of essential medicines. The release cited statements by David A. Lorch, Director of the Office of Strategic Capital; Akshaya Trivedi, Managing Director for Investments; and Emil Michael, Under Secretary of War for Research and Engineering, saying the investment would strengthen the security and resilience of America's pharmaceutical supply chain.
The commitment remains conditional: before the loan can close, Antheia must still satisfy financial, legal, technical and other due diligence requirements. The Office of Strategic Capital is the department's financing arm, tasked with using loans and other tools to crowd in private capital for critical supply-chain technologies tied to national security. (GSM, compiled from the Department of War's release.)
发布：GSM·美国（发布链接）
图片来源：图：五角大楼航拍（美国战争部总部，位于弗吉尼亚州 Arlington，隔 Potomac 河与华盛顿相望）。美国海军照片，公共领域。Aerial view of the Pentagon, headquarters of the U.S. Department of War in Arlington, Virginia. U.S. Navy photo, public domain.
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