玫瑰花瓣合成三氧化二砷纳米颗粒 对多重耐药大肠杆菌最低抑菌浓度 100 微克每毫升
11 月 14 日发表于《科学报告》的一项研究用粉红玫瑰花瓣生物合成三氧化二砷纳米颗粒，并测试其对多重耐药大肠杆菌的抑制作用。研究作者为 Ghaderi、Pajavand 与 Satarzadeh 等人，玫瑰花瓣在合成中用作还原剂。
合成颗粒呈球形，扫描电镜测得平均干粒径为 17.74 纳米，动态光散射测得水动力直径为 19.01 纳米。最低抑菌浓度方面，对标准菌株为 50 微克每毫升，对多重耐药临床菌株为 100 微克每毫升。
作者表示，该颗粒的生物安全性与更广的抗菌谱仍需进一步评估。本研究无专项资助。
Rose-Petal-Synthesized Arsenic Trioxide Nanoparticles Show MIC of 100 Micrograms per Milliliter Against Multidrug-Resistant E. coli
A study published November 14 in Scientific Reports used pink rose petals to biosynthesize arsenic trioxide nanoparticles and tested them against multidrug-resistant Escherichia coli. The authors are Ghaderi, Pajavand, Satarzadeh, and colleagues; the rose petals served as the reducing agent in the synthesis.
The particles were spherical, with a mean dry diameter of 17.74 nanometers by scanning electron microscopy and a hydrodynamic diameter of 19.01 nanometers by dynamic light scattering. The minimum inhibitory concentration was 50 micrograms per milliliter against the standard strain and 100 micrograms per milliliter against the multidrug-resistant clinical strain.
The authors state that the particles' biosafety and broader antibacterial spectrum require further evaluation. The study received no dedicated funding.
来源：《科学报告》
发布：GSM·美国（发布链接）
图片来源：图：一朵盛开的黄玫瑰；本研究以玫瑰花瓣为还原剂生物合成纳米颗粒。来源：Roman Köhler，Wikimedia Commons，Public domain。 / Photo: A yellow rose in bloom; the study used rose petals as the reducing agent to biosynthesize the nanoparticles. Source: Roman Köhler, Wikimedia Commons, Public domain.
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