跟进：加州 San Luis Obispo 南瓜农场大肠杆菌疫情确认 1 人死亡，县方结案未查明污染源
加利福尼亚州圣路易斯-奥比斯波县公共卫生局 11 月 10 日确认，一名与 Brookshire Farms 南瓜农场大肠杆菌 O157 疫情关联的人已经死亡，这是这起疫情的首例死亡。事发农场位于该县 San Luis Obispo 市 Los Osos Valley Road 4747 号。
县公共卫生局发言人 Tom Cuddy 11 月 10 日对当地媒体表示：「我们可以确认，一名与这起大肠杆菌疫情关联的个人已经死亡。我们是在其家属同意下发布这一消息。」县方向死者家属致哀，但没有公布死者的年龄与身份，也没有说明死者属于 5 名实验室确诊病例还是 10 名疑似病例中的一员。
县公共卫生局此前的发布显示，5 名实验室确诊的产志贺毒素大肠杆菌 O157 感染者都曾在 10 月 17 日或 18 日到访这家农场；另有 10 人在 10 月 16 日至 26 日之间到访后出现症状，被列为疑似病例。据县方 10 月 30 日的发布，其中 3 名儿童并发溶血性尿毒综合征，入住儿科重症监护；据当地媒体报道，一名来自 Nipomo 的 6 岁男童病情危重，在斯坦福 Lucile Packard 儿童医院接受救治。县方没有说明死者是否为这 3 名儿童之一。
县公共卫生局已于 11 月 6 日宣布调查收尾。调查结论显示，3 名患者体内的菌株基因一致，且与全国数据库中的已知菌株不相近，强烈提示存在一个共同且独特的污染源；但在农场采集的水、食物与其他环境样本中没有检出大肠杆菌 O157，具体污染源未能查明。患者共同接触过的物品包括可食用玉米杯、南瓜、干草与非饮用水源；农场内没有对公众开放的农场动物或动物互动区。县卫生局局长 Christy Mulkerin 表示，这起事件的追加暴露风险已经过去，目前不存在持续的公共卫生威胁，县方不计划再追加环境检测。
Brookshire Farms 在 10 月 27 日起自愿关闭，11 月 6 日重新开放。农场方面称，自家检测与环境样本对疫情菌株呈阴性。据当地电视台 KSBY 与《圣路易斯奥比斯波论坛报》报道，农场联合所有人 Shawn Callaway 表示，他对受影响的家庭深感痛心，并认为南瓜不是污染源，称县方没有检测农场的南瓜。
GSM 曾于 10 月 29 日报道这起疫情的调查进展，当时 5 例确诊、3 名儿童重症，农场自愿关闭。
关联：加州圣路易斯-奥比斯波县南瓜园大肠杆菌调查：5例确诊、3名儿童重症入住儿科重症监护，农场自愿关闭至南瓜季结束
Follow-Up: First Death Confirmed in San Luis Obispo Pumpkin Farm E. coli Outbreak; County Closes Probe Without Finding Source
The San Luis Obispo County Public Health Department in California confirmed on November 10 that one person associated with the E. coli O157 outbreak linked to Brookshire Farms has died, the first death in the outbreak. The farm is located at 4747 Los Osos Valley Road in the city of San Luis Obispo, San Luis Obispo County.
"We can confirm that one individual associated with the E. coli outbreak has died. We are sharing this information with the permission of the individual's family," department spokesman Tom Cuddy told local media on November 10. The county offered its condolences but did not release the person's age or identity, and did not say whether the person was one of the five laboratory-confirmed cases or one of the ten suspect cases.
According to the county's earlier releases, all five people with laboratory-confirmed Shiga toxin-producing E. coli O157 infection visited the farm on October 17 or 18, and ten more people who visited between October 16 and 26 and developed symptoms were counted as suspect cases. The county's October 30 release reported that three children had developed hemolytic uremic syndrome and were in pediatric intensive care; local media reported that a 6-year-old boy from Nipomo was in critical condition at Stanford's Lucile Packard Children's Hospital. The county has not said whether the person who died was one of those three children.
The county announced on November 6 that it was wrapping up its investigation. Investigators found that the bacterial strains in three of the patients were a genetic match and did not closely match known strains in national databases, strongly suggesting a common and unique source; however, testing of water, food and other environmental samples collected at the farm did not find E. coli O157, and the specific source was not identified. Exposures common to the patients included edible corn cups, pumpkins, hay and non-potable water sources, and the farm had no farm animals or petting zoo open to the public. County Health Officer Dr. Christy Mulkerin said the risk of additional exposure has passed, there is no ongoing public health threat, and no additional environmental testing is planned.
Brookshire Farms closed voluntarily starting October 27 and reopened on November 6. The farm said its own tests and environmental samples came back negative for the outbreak strain. According to KSBY and The Tribune of San Luis Obispo, co-owner Shawn Callaway said he was heartbroken for the affected families and did not believe pumpkins were the source, saying the county had not tested the farm's pumpkins.
GSM first reported on this outbreak investigation on October 29, when five cases had been confirmed, three children were seriously ill and the farm had closed voluntarily.
来源：圣路易斯-奥比斯波县公共卫生局
发布：GSM·美国（发布链接）
图片来源：图：加州一处南瓜园（资料图，非涉事农场）。inkknife_2000 摄，CC BY-SA 2.0，经 Wikimedia Commons。 / Photo: A pumpkin patch in California (file photo; not the farm involved in this story). By inkknife_2000, CC BY-SA 2.0, via Wikimedia Commons.
GSM Global · 本篇英文版 English edition of this story
- 2026-10-29 02:09加州圣路易斯-奥比斯波县南瓜园大肠杆菌调查：5例确诊、3名儿童重症入住儿科重症监护，农场自愿关闭至南瓜季结束
- 2026-11-11 21:19跟进：加州 San Luis Obispo 南瓜农场大肠杆菌疫情确认 1 人死亡，县方结案未查明污染源本篇
