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宾夕法尼亚州维拉诺瓦大学库恩斯获NIH五年期357万9,843美元拨款:研究照护者如何影响肺移植患者结果,将招募410对患者—照护者、术后6与12个月评估,拨款编号R01HL184123

2026-11-09 · 医疗 · GSM News
宾夕法尼亚州维拉诺瓦大学库恩斯获NIH五年期357万9,843美元拨款:研究照护者如何影响肺移植患者结果,将招募410对患者—照护者、术后6与12个月评估,拨款编号R01HL184123

宾夕法尼亚州维拉诺瓦市消息—维拉诺瓦大学(Villanova University)10月15日发布,该校 M·路易丝·菲茨帕特里克护理学院护理学助理教授布列塔尼·库恩斯(Brittany Koons)博士获美国国立卫生研究院(NIH)国家心肺血液研究所(NHLBI)五年期拨款3,579,843美元,研究照护者如何影响肺移植患者的结果,以期为移植项目如何评估与支持患者及家庭提供证据。

据该校发布,多达20%的移植候选人因照护支持不足被认定不符合资格,而照护者究竟如何影响移植结果、什么构成充足支持,现有证据有限。库恩斯表示,若移植流程继续要求照护者参与,就必须理解其作用、其对结果的影响以及如何更好地支持患者与照护者双方。

研究以医学复杂程度最高的器官移植之一—肺移植为对象,把移植照护作为患者与照护者的双人伙伴关系来研究:团队将于移植前招募410对患者—照护者,经移植全程随访,并在术后6个月与12个月评估,衡量双方对移植照护的贡献如何影响生存、住院、生活质量、照护者负担与照护者福祉,并辅以分别访谈的混合方法设计。参与者经宾夕法尼亚大学、哥伦比亚大学与加州大学旧金山分校的移植中心招募,项目借用 NHLBI 资助的肺移植联盟 PROMISE 研究的基础设施。本研究由 NHLBI 拨款 R01HL184123 全额联邦资助,金额3,579,843美元。

Villanova University's Brittany Koons in Villanova, Pennsylvania Wins a Five-Year, $3,579,843 NIH Grant: Studying How Caregivers Affect Lung Transplant Outcomes, Enrolling 410 Patient-Caregiver Dyads With Assessments at Six and 12 Months After Surgery, Under Award R01HL184123

VILLANOVA, Pennsylvania — Villanova University reported on October 15 that Brittany Koons, PhD, RN, assistant professor of Nursing in the M. Louise Fitzpatrick College of Nursing, has received a five-year, $3,579,843 grant from the National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH) to investigate how caregivers influence outcomes for lung transplant patients and to develop evidence that could reshape how transplant programs evaluate and support patients and families.

According to the university, while transplants can significantly extend survival and improve quality of life, as many as 20 percent of transplant candidates are considered ineligible because of inadequate caregiver support, and there is limited evidence explaining exactly how caregivers affect transplant outcomes or what constitutes adequate support. Koons said that if caregivers continue to be required as part of the transplant process, their role, their impact on outcomes and how to better support both patients and caregivers need to be understood.

The study focuses on lung transplantation, one of the most medically complex organ transplants, and studies transplant care as a dyadic partnership between patients and caregivers. The team will enroll 410 patient-caregiver dyads before transplant, follow them through transplantation and conduct assessments six and 12 months after surgery, evaluating how the pair's contributions affect survival, hospitalization, quality of life, caregiver burden and caregiver well-being, in a mixed-methods design that also includes separate in-depth interviews. Participants will be recruited through transplant centers at the University of Pennsylvania, Columbia University and the University of California, San Francisco, leveraging the infrastructure of the NHLBI-funded Lung Transplant Consortium PROMISE Study. The research is supported by NHLBI under Award Number R01HL184123 and is 100 percent federally funded in the amount of $3,579,843.

来源链接:维拉诺瓦大学发布(villanova.edu,2026-10-15): https://www.villanova.edu/university/media/press-releases/2026/nursing-grant.html

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图片来源:Wikipedia/Wikimedia Commons 词条主图:Brittany

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