伊利诺伊州芝加哥Yoga-CaRe心衰试验：3492名患者瑜伽心脏康复3个月生活质量多升8.1分、6分钟多走25.5米，死亡住院卒中复合率21.0%对22.8%无显著差异
伊利诺伊州库克县芝加哥市消息—11月7日在芝加哥举行的美国心脏协会2026年科学年会上公布的 Yoga-CaRe HF 试验结果显示，以瑜伽为基础的心脏康复项目改善了射血分数降低型心力衰竭（HFrEF）患者的生活质量与步行能力，但未显著降低死亡、住院或卒中的复合发生率。据会议报道，该试验在印度16个医疗中心随机入组3492名成年人，其中瑜伽组1737人、强化标准护理组1755人，于2023年4月至2025年12月招募，患者包括射血分数在40%及以下的 HFrEF 患者。
干预方面，瑜伽组接受书面健康教育、行为改变与目标设定协助，以及3个月内20次由专业人员指导的课程（含面授、线上与居家练习）。3个月时，瑜伽组的明尼苏达心衰生活质量量表（MLHFQ）评分较对照组多改善约8.1分，6分钟步行距离平均多25.5米，EQ-5D 效用量表均值差为0.05，三项比较的研究报告均为 P<0.001。中位随访15个月内，瑜伽组有21.0%的患者发生死亡、住院或卒中，对照组为22.8%，风险比0.90，差异无统计学显著性，该共同主要终点未达到。
该研究由印度慢性病控制中心执行主任多赖拉杰·普拉巴卡兰（Dorairaj Prabhakaran）报告、安巴拉姆·钱德拉塞卡兰（Ambalam Chandrasekaran）在会场作迟发科学报告。美国心脏协会提示，科学会议上报告的摘要未经同行评审，在同行评审期刊正式发表前应视为初步发现。
Yoga-CaRe Heart Failure Trial in Chicago, Illinois: 3,492 Patients Gained 8.1 Quality-of-Life Points and 25.5 Metres on the Six-Minute Walk at Three Months, With No Significant Difference in Death, Hospitalization or Stroke at 21.0% Versus 22.8%
CHICAGO, Cook County, Illinois — Results of the Yoga-CaRe HF trial, presented on November 7 at the American Heart Association's Scientific Sessions 2026 in Chicago, showed that a supervised yoga-based cardiac rehabilitation programme improved quality of life and walking capacity in patients with heart failure with reduced ejection fraction (HFrEF), but did not significantly reduce the combined rate of death, hospitalization or stroke. According to the meeting coverage, the trial randomized 3,492 adults at 16 medical centres in India — 1,737 to the yoga group and 1,755 to enhanced standard care — recruiting between April 2023 and December 2025, including patients with an ejection fraction of 40% or below and patients hospitalized for acute decompensated heart failure.
The yoga group received written health education on living well with heart failure, guided behaviour change and goal-setting assistance, plus 20 supervised sessions over three months combining in-person, virtual and at-home instruction. At three months, the yoga group's Minnesota Living with Heart Failure Questionnaire scores improved by about 8.1 points more than the control group's, participants walked an average of 25.5 metres farther on the six-minute walk test, and the mean difference in EQ-5D utility score was 0.05, with P<0.001 reported for all three comparisons. Over a median follow-up of 15 months, 21.0% of the yoga group and 22.8% of the control group reached the composite endpoint of death, hospitalization or stroke — a hazard ratio of 0.90 that was not statistically significant, so that co-primary endpoint was not met.
The study was presented by Dorairaj Prabhakaran, M.B.B.S., M.D., D.M., executive director of the Centre for Chronic Disease Control in India, with Ambalam Chandrasekaran reporting the late-breaking science. The American Heart Association notes that abstracts presented at its scientific meetings are not peer-reviewed and that findings are considered preliminary until published in a peer-reviewed journal. This report presents only the trial data and the investigators' statements and does not constitute medical advice for any individual.
来源链接：美国心脏病学会会议报道（acc.org）： https://www.acc.org/latest-in-cardiology/articles/2026/11/06/14/37/sat-5pm-yoga-aha-2026 ；试验报道（tctmd.com）： https://www.tctmd.com/news/yoga-care-qol-and-functional-gains-seen-hfref-patients
来源：美国心脏协会
发布：GSM·美国（发布链接）
图片来源：图：瑜伽课堂。Yogacharya Rajendra 摄，CC BY-SA 4.0，经 Wikimedia Commons。 / Photo: A yoga class. Photo by Yogacharya Rajendra, CC BY-SA 4.0, via Wikimedia Commons.
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