65岁以上打流感疫苗怎么选：CDC优先推荐高剂量、重组或佐剂疫苗
本季流感活动已经起步，不少长者去药房打疫苗时会发现流感疫苗有好几种。美国疾病控制与预防中心（CDC）9月1日发布的2026–27季临床指引确认，2025年7月免疫规划中的建议在本季继续有效：65岁以上人群应优先接种三种「加强型」流感疫苗中的任意一种。
三种加强型疫苗分别是：高剂量灭活疫苗（Fluzone High-Dose），抗原含量是普通剂量的四倍；重组疫苗（Flublok），不经鸡蛋培养；以及含佐剂的灭活疫苗（Fluad），佐剂的作用是帮助激发更强的免疫反应。CDC的研究评估显示，这三类疫苗对65岁以上人群的保护效果可能优于普通剂量疫苗，这也是优先推荐的原因。
CDC同时提醒，如果接种点暂时没有这三种疫苗，不要为了等加强型而推迟接种，任何适合年龄的流感疫苗都可以打，尽早形成保护更重要。6个月以上的几乎所有人都应每年接种流感疫苗；本季在美国使用的流感疫苗均为三价疫苗。眼下流感季已经开始，尚未接种的长者可向药房或家庭医生询问加强型疫苗的供应情况。（来源：美国疾病控制与预防中心）
Choosing a Flu Shot After 65: CDC Preferentially Recommends High-Dose, Recombinant or Adjuvanted Vaccines
With this flu season already under way, many older adults find several flu vaccine options at the pharmacy. The CDC's clinical guidance for the 2026-27 season, issued September 1, confirms that the recommendations in the July 2025 immunization schedule remain in effect: adults 65 and older should preferentially receive one of three enhanced flu vaccines.
The three enhanced options are the high-dose inactivated vaccine (Fluzone High-Dose), which contains four times the antigen of a standard dose; the recombinant vaccine (Flublok), which is not grown in eggs; and the adjuvanted inactivated vaccine (Fluad), whose adjuvant is designed to promote a stronger immune response. CDC's evidence review suggests these vaccines may protect people 65 and older better than standard-dose vaccines, which is why they are preferentially recommended.
The CDC also cautions that if none of the three is available, older adults should not delay vaccination to wait for one; any age-appropriate flu vaccine is better than none, and getting protected early matters more. Nearly everyone 6 months and older should get a flu vaccine every year, and all flu vaccines used in the United States this season are trivalent. With the season already under way, older adults who have not yet been vaccinated can ask their pharmacy or doctor about availability of the enhanced vaccines. (Source: Centers for Disease Control and Prevention)
来源：美国疾病控制与预防中心
发布：GSM·美国（发布链接）
图片来源：图片来源：流感疫苗接种现场（U.S. Air Force photo by Senior Airman Greydon Furstenau 摄，Wikimedia Commons，Public domain） / Image: A flu vaccination clinic, by U.S. Air Force photo by Senior Airman Greydon Furstenau, Wikimedia Commons (Public domain)
GSM Global · 本篇英文版 English edition of this story
