布拉瓦特尼克家庭基金会资助耶鲁医学院1,000万美元:启动炎症科学研究计划

位于美国康涅狄格州纽黑文县纽黑文市(New Haven, New Haven County, Connecticut)的耶鲁大学医学院宣布,获得布拉瓦特尼克家庭基金会(Blavatnik Family Foundation)1,000万美元资助,启动一项炎症科学研究计划,并设立研究生与博士后研究员项目。
炎症是免疫系统对感染与损伤的反应,一旦失控、误伤健康组织,就会发展成几乎可累及任何器官的慢性炎症,与多种疾病相关。新计划将专门研究支配炎症的基本原理,以及健康与疾病状态下免疫发育的根本机制。
计划由免疫生物学 Sterling 讲席教授 Ruslan Medzhitov 担任主任,他在先天免疫系统方面的开创性发现重塑了学界对炎症的理解;共同领导的还有 Noah Palm、Liza Konnikova 与 Akiko Iwasaki 等耶鲁学者。团队将跨学科研究感染、环境因素与肠道微生物群如何影响炎症,寻找连接表面上互不相关疾病的生物学原理。
资助的另一重点是人才培养:新设的「布拉瓦特尼克研究生与博士后研究员」项目将支持下一代炎症研究者。医学院院长 Nancy J. Brown 表示,炎症是当今几乎每种疾病的底层因素,厘清其机制可以改变未来几代人的医学。
基金会创始人 Len Blavatnik 表示,耶鲁医学院的科学家在炎症科学上独具优势、有望取得新突破。该基金会支持耶鲁炎症研究已超过十年,此前的资助已带来从炎症调控基本原理到肠道、免疫系统与大脑相互作用等多项进展。
Blavatnik Family Foundation Gives Yale School of Medicine $10 Million to Launch an Inflammation Science Initiative
Yale School of Medicine in New Haven, New Haven County, Connecticut, has announced a $10 million grant from the Blavatnik Family Foundation to launch a new research initiative in inflammation science, which will also fund graduate and postdoctoral fellowships.
Inflammation is the immune system's response to infection and injury; when it misfires and damages healthy tissue, it can become chronic and affect almost any organ or system. The new initiative will be dedicated to understanding the fundamental principles that govern inflammation and the fundamental mechanisms of immune development in health and disease.
The initiative will be directed by Ruslan Medzhitov, Sterling Professor of Immunobiology, whose groundbreaking discoveries about the innate immune system reshaped the field. He will lead the work alongside Yale colleagues Noah Palm, Liza Konnikova and Akiko Iwasaki. Bringing together researchers across disciplines, the team will examine how infection, environmental factors and the microbiome influence inflammation, seeking biological principles that connect seemingly unrelated conditions.
A key component of the grant is the new Blavatnik Graduate and Postdoctoral Fellows program, which will build a pipeline of talent dedicated to inflammation science. 'We are grateful for the Blavatnik Family Foundation's vision and generosity,' said Nancy J. Brown, dean of Yale School of Medicine. 'Inflammation underlies nearly every disease we face today, and unraveling mechanisms of inflammation in health and disease can transform medicine for generations to come.'
'Yale School of Medicine's exceptional scientists are uniquely positioned to break new ground in inflammation science,' said Len Blavatnik, founder of the Blavatnik Family Foundation. The foundation has supported inflammation science at Yale for more than a decade, enabling advances from the basic principles that control inflammation to the systemic interactions between the gut, the immune system and the brain.
Yale School of Medicine official announcement
来源:GSM·美国(原文链接)
图片来源:耶鲁医学院(资料图)。ajay_suresh 摄,CC BY 2.0,经 Wikimedia Commons。 / Yale School of Medicine (file photo). Photo by ajay_suresh, CC BY 2.0, via Wikimedia Commons.
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