克里斯蒂娜·阿普尔盖特播客复出自述：2021年多发性硬化系误诊，症状未消称「回到原点」
54岁的美国演员克里斯蒂娜·阿普尔盖特（Christina Applegate）10月20日在她与 Jamie-Lynn Sigler 共同主持的播客《MeSsy》复出时透露，医生近日告诉她，她2021年被诊断出的多发性硬化（multiple sclerosis，MS）系误诊，她实际上并不患有这种疾病。据《今日美国报》（USA Today）报道，这是她在今年早些时候住院数月、离开公众视线约七个月后，首次以两集连播的形式回到这档以「与MS共处」为主题的播客。
阿普尔盖特在节目中含泪回忆，医生走进她的房间说：「恭喜你，你没有多发性硬化。」她说自己「一点也不高兴」，周围的人却都很高兴。她说：「被误诊之后，人不会突然就好了。我没有好转，有些方面反而更糟了。我回到了原点，根本不知道自己到底怎么了。」她表示，自己的症状与MS患者「一模一样、每一条都对得上」，医生接下来将继续追查自2021年以来她身体究竟出了什么问题；据 Parade 报道，她目前仍需依靠轮椅完成从车边到诊室门口这样的短距离移动。
她坦言，这次误诊让她陷入抑郁，也让她觉得自己「让所有人失望了」：她和同患MS的 Sigler 这些年一直是MS群体的公众代言人。她在第二集节目中说，自己如今感到「空落落的，又害怕又难过」，「现在，我只觉得迷失了方向」。Sigler 在节目中安慰她说，她没有误导任何人。
第二集节目请来了 Cedars-Sinai 医疗中心神经科副教授 Marwa Kaisey 医生。据 LADbible 报道，Kaisey 在节目中表示，MS误诊并不罕见，原因之一是没有哪一项单一检测能确诊MS，诊断依靠的是一组标准；据她在节目中引述的数据，约有两成被诊断为MS的人最终被发现并非患有该病。阿普尔盖特的真实病因目前尚未公布，她的医疗团队将重新排查。
阿普尔盖特2021年在拍摄 Netflix 剧集《麻木不仁》（Dead to Me）最后一季期间确诊「MS」，此后宣布退出幕前演出，并通过回忆录与《MeSsy》播客持续公开自己的健康历程。她在节目中表示，过去她至少知道「为什么每一天都这么难熬」，如今连这个解释也没有了，「非常令人不安，也非常令人困惑」。（GSM 据《今日美国报》报道）
Christina Applegate Says Her 2021 MS Diagnosis Was a Misdiagnosis: 'Back at Square One'
Christina Applegate, 54, revealed on the October 20 return of MeSsy, the podcast she co-hosts with Jamie-Lynn Sigler, that doctors recently told her the multiple sclerosis (MS) she was diagnosed with in 2021 was a misdiagnosis and that she does not have the disease. According to USA Today, the two-part episode marked her return to the podcast, which is devoted to living with MS, after she spent several months in the hospital earlier this year and about seven months away from public view.
Applegate tearfully recalled her doctor coming into her room and saying, "Congratulations, you don't have MS." She said she was "not happy at all," even though everyone else was happy. "You don't get misdiagnosed and then all of a sudden I'm better. I haven't gotten better. If anything, I've gotten worse in some ways. So I'm back at square one, that I don't know what's going on with me," she said. She said she had "every symptom" of someone with MS, and that her doctors will keep investigating what has been happening to her since 2021. Parade reported that she still relies heavily on a wheelchair for basic mobility, including getting from her car into a doctor's office.
She said the revelation plunged her into depression and left her feeling she had "let everybody down," after she and Sigler, who has MS, became prominent public faces of the MS community. In the second part, she said she felt "quite hollow and quite scared and sad," adding, "Now, I just feel lost." Sigler assured her on the show that she had not misled anyone.
The second episode featured Dr. Marwa Kaisey, an associate professor of neurology at Cedars-Sinai Medical Center. According to LADbible, Kaisey said on the podcast that MS misdiagnoses are fairly common, in part because there is no single test for MS and diagnosis rests on a list of criteria; she cited a figure of about 20 percent of people diagnosed with MS ultimately turning out not to have it. What condition Applegate actually has has not been publicly confirmed, and her doctors will investigate anew.
Applegate was diagnosed with what was believed to be MS in 2021 while filming the final season of the Netflix series Dead to Me, after which she stepped back from on-screen acting and continued to document her health journey in a memoir and on MeSsy. She said she once at least had a reason "as to why my day sucked every day," and that losing that explanation is "very unnerving" and "really confusing." (GSM, based on USA Today reporting)
发布：GSM·美国（发布链接）
图片来源：Christina Applegate资料照片（2014年7月25日圣迭戈国际动漫展摄，非本次播客录制现场），Gage Skidmore摄，Wikimedia Commons，CC BY 2.0授权
GSM Global · 本篇英文版 English edition of this story
