洛杉矶县确认首例cychlorphine致死病例 新型合成阿片药效强于芬太尼
洛杉矶县公共卫生局近日发布声明，县法医办公室已确认一例发生于2026年2月的死亡与新型合成阿片类药物cychlorphine有关，这是该药物在洛杉矶县非法毒品供应中首次被证实存在。
县公共卫生局表示，cychlorphine的化学名称为N-propionitrile chlorphine，药效强于芬太尼，极少量即可使人停止呼吸；该药物目前无法被芬太尼试纸检出，且常在使用者不知情的情况下被掺入非法毒品，以粉末、假处方药片、结晶或液体等形式流通。该药物2024年首次在美国被发现，此后已在19个州检出；加州首例相关死亡今年4月出现在北加州。美国缉毒局已于今年8月将chlorphine列为一级管制物质，禁止持有与销售。
县公共卫生局表示，过量逆转药物纳洛酮（Narcan）对cychlorphine同样有效，可经鼻腔或肌肉注射给药，紧急情况下可能需要多次给药，并应立即拨打911。该局称正持续监测本地非法毒品供应中这一药物的流通变化。
L.A. County Confirms First Death Linked to Cychlorphine, a Synthetic Opioid Stronger Than Fentanyl
The Los Angeles County Department of Public Health says the county Medical Examiner has identified the synthetic opioid cychlorphine as a cause of a death that occurred in February 2026 — the first confirmation of the drug's presence in the county's illicit drug supply.
Cychlorphine, or N-propionitrile chlorphine, is more potent than fentanyl, and a very small amount can stop a person's breathing, the department said. It cannot be detected by fentanyl test strips and is being mixed into the illicit drug supply without users' knowledge, appearing in powders, counterfeit prescription pills, crystals and liquids. First detected in the United States in 2024, the drug has since been identified in 19 states; California's first linked death was reported in Northern California in April. The U.S. Drug Enforcement Administration classified chlorphine as a Schedule I controlled substance in August.
Naloxone can reverse overdoses involving cychlorphine, though multiple doses may be necessary, and anyone witnessing an overdose should call 911, the department said. Public Health says it is monitoring the local drug supply for changes in the drug's prevalence.
发布：GSM·美国（发布链接）
图片来源：图：纳洛酮注射急救包。图片来源：MohammedLombardia，Wikimedia Commons，CC BY-SA 4.0。Photo: A naloxone injection kit. Image: MohammedLombardia, via Wikimedia Commons, CC BY-SA 4.0.
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